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Antimicrobial resistance

Addressing global public health challenges, by developing a quantum computing solution to improve current AI models, predict more quickly and accurately patterns of resistance and identifying new chemical compounds with low resistance on more targeted bacteria.

OWNER

Curated by OQI

STATUS

Outline of the use case

CONTRIBUTORS

University of Copenhagen Alphanosos
GARDP

SDGs

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IMPACT/ CONTEXT

WHO declared antimicrobial resistance (AMR) as one of the top ten threats to global public health.  

Low- and middle- income countries, and certain population groups such as children and the elderly, are hit the hardest by AMR. AMR also has an economic cost, as it affects productivity and economic growth. The World Bank estimates that if AMR is unchecked, by 2030, an additional 24.1 million people could be forced into extreme poverty.

Despite the significant economic, environmental, and societal costs, the development of new antimicrobials has not kept pace with the emergence of resistance, leaving healthcare providers with fewer options for treating infections. No new classes of antibiotics have been discovered in the past decades. 

 

HOW QUANTUM COULD HELP

An approach to AMR research is to identify new drugs that have more targeted action to specific diseases and that are efficient against any known resistance mechanism. Machine learning methods are used to find new and efficient combination of compounds. Such predictive models learn relationships between large chemical diversity found in libraries of chemical compounds and experimental in vitro observations, and then predict novel mixes with improved efficacies (in terms of targeted disease treatment and resistance).

A quantum computing solution, based on quantum machine learning, could potentially be developed as an alternative or complement to classical machine learning algorithms for the prediction of patterns of resistance and of new chemical compounds with low resistance on more targeted bacteria. The key goal would be to obtain higher-quality mixes with fewer experimentation-learning cycles, as the number of cycles involves expensive on-demand experiments.

2024 | Open Quantum Institute

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Join the Future of Quantum Computing!

Learn about engagement opportunities

OQI Partners are institutions that benefit from peer recognition for their scientific contributions or impact expertise.

Requirements:

  1. Either have served as OQI’s spearheading partners during its incubation phase or have consistently engaged resources to OQI’s work as OQI members for at least a year
  2. Commit to co-shape the OQI’s unique value propositions for the three years of the pilot throughout the 4A’s​
  3. Are vetted by the OQI Advisory Committee
  4. Abide to OQI’s values and openness principles

OQI Members are institutions that benefit from peer recognition for their scientific contributions or their impact expertise.

Requirements:

  1. Have disclosed their governance structure
  2. Commit to actively contribute on at least one of the 4A’s assiduously for at least one year​
  3. Have appointed at least one expert from their institution as focal point of contact for OQI and contributor to its working groups
  4. Abide to OQI’s values
  5. Have submitted a complete membership form with supporting documentation and are vetted by the OQI Management Team
  6. Qualify for partner level after having demonstrated their commitment for at least one year​

OQI Friends are individuals (such as experts from the private or public sector, countries, citizens) who are committed to open science, inclusivity and all values as set out in OQI’s charter and associate themselves with the OQI.

Friends socialise the OQI to their communities.

Downloadable PDF version of Charter

 

Description:

The Open Quantum Institute (OQI) is a multilateral governance initiative that promotes global and inclusive access to quantum computing and the development of applications for the benefit of humanity. As a novel science diplomacy instrument, it brings together research, diplomacy, private sector and philanthropy stakeholders. OQI is hosted by CERN during its pilot phase (2024-2026).

 

Mission:

• Accelerating applications for humanity: Realising the full potential of quantum computing to have the widest possible societal impact by accelerating the development of use cases geared towards achieving the United Nations’ Sustainable Development Goals (SDGs) and succeeding framework , thanks to the combined forces of researchers, developers and entrepreneurs from academia and private sector as well as the United Nations, and large NGOs
• Access for all: Providing global, inclusive and equitable access to a pool of public and private quantum computers and simulators available via the cloud
• Advancing capacity building: Developing educational tools to enable everyone around the world to contribute to the development of quantum computing and make the most of the technology
• Activating multilateral governance for the SDGs: Providing a neutral forum to help shape multilateral governance of quantum computing for the SDGs

 

Values:

• Inclusivity, global scope
  • Enable people from all countries, regardless of whether they have any quantum computing capability of their own, to benefit from and to participate in the development of (i) quantum computing applications that address global challenges, in particular those that are closely related to their own specific challenges, and (ii) the multilateral governance of quantum computing for the SDGs
• Openness
  • Share experiences, knowledge, and methods for the benefit of all, following Open Science best practice
  • Make openly available the results – outcomes of joint activities related to the OQI mission conducted by the OQI community – to society via open repositories and/or through the use of open licences
• Focus on impact
  • Ensure that applications are developed for their quantum computing potential to tackle real-world problems that will benefit humanity
  • Consider and balance their ethical, legal, and societal implications
• Independence
  • Enable everyone to participate free from individual, national, corporate or any other agendas
  • Develop applications with a technology neutral approach.
• Collaboration
  • Foster a community of diverse expertise, backgrounds and geographies, enabled by international cooperation and diplomacy

 

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